The Wounded Lung

The most important complication of a needle lung biopsy is a pneumothorax, meaning air leaks from the lung into the space between the lung and chest wall. This can cause part of the lung to collapse. Many pneumothoraces are small and resolve with observation, but a larger one may require insertion of a chest tube to remove the air and allow the lung to re-expand. One large NHS center’s patient guidance reports small pneumothoraces in up to roughly 25% of CT-guided biopsies and chest-drain placement in around 5%, although rates vary substantially depending on the patient’s lungs, lesion location, needle path, and technique.
Bleeding is another important risk. A small amount of bleeding inside the lung or coughing up a small amount of blood can occur after a biopsy. Serious hemorrhage is uncommon. Infection can occur but is relatively unusual. Bronchoscopic biopsies can also cause bleeding, pneumothorax, reactions to sedative or anesthetic medicines, temporary decreases in oxygen levels, or fever.



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